INDEX (see report)

Admissions Number in EpicLatino 2019 18

ANTIBIOTIC days

Median and Interquartile ranges of in infants < 33 weeks GA at birth by Unit controlled by Gestational Age 204-205

Use and Total Number of Infections x 1000 Days of stay in Infants < 33 weeks GA at birth and discharged home by Unit 206-207

Use in Infants < 33 weeks GA at birth, by Unit in 3 Gestational Age Groups 203

Catheter

Arterial and Venous Umbilical Median Days (in Children with GA <33 Weeks) by gestational age groups and units 196-197

Median ± IQR Days with (in infants GA <33 weeks) by Unit. 194-195

Chest tube for Pneumothorax in EpicLatino 2019 46-47

Cultures Positive during catheter use per 1000 Catheter Days in Infants <33 weeks GA according to catheter type 115-116

Discharge

Destination (All Patients) 170-171

Support in survivors 172-173

EpicLatino network coordinating neonatal center 1

Gestational Age (GA) in EpicLatino 2019 24-25

Hemorrhage Intraventricular

Grade 1 and 2 versus 3 and 4 by GA at birth in EpicLatino 2019 58

Graph 117-118

ODDS RATIO Neuroimaging Anomalies in infants < 33 weeks GA by UNIT. 120-121

In Germinal Matrix and Ventricles by GA at birth in EpicLatino 2019 57

III and IV Intraventricular in infants < 33 weeks GA by unit 122-127

Indomethacin Prophylactic in EpicLatino 2019 46-47

Invasive mechanical ventilation

days (in infants GA <33 weeks) 175-176

Median Regression days in (in infants GA <33 weeks) Adjusted by GA at birth by Units 177

Laser /Anti-VEGF

Therapy in infants with Retinopathy of Prematurity by GA (table) 78

 < 1500 g by BW 79-80

Latin American Epiq Neonatal Network Foundation 1

Maternal Characteristics in EpicLatino 2019 31-33

Morbidities by GA in ≤ 32w at birth (Six Morbidities) 80-81

Mortality

Crude Comparison in <33 weeks GA at birth at Different Units (graph) 101-102

Odd Ratio (Adjusted by SNAPEPE II and GA by unit in less than 33 weeks GA 104-105

NECROTIZING ENTEROCOLITIS (Stage ≥ 2) in Infants <33 weeks GA

Treatment Modalities by GA at Birth in EpicLatino 2019 62-63

by BW 64-65

by UNIT 128-129

Odds Ratio (Stage ≥ 2) in < 33 weeks GA Adjusted by SNAPEPE II and GA (By UNITS) 131-132

Needle Paracentesis for Pneumothorax in EpicLatino 2019 46-47

Neuroimaging Anomalies

in EpicLatino 2019 56

in infants < 33 weeks GA by UNIT. 117

NON-Invasive Ventilation

Average Days by Unit in < 33 weeks GA 179

Median of Days Over Invasive Ventilation Days by Unit in < 33 weeks GA 183-184

Median Regression Days in by unit in < 33 weeks GA 181-182

Over invasive mechanical ventilation days by unit and by GA groups in < 33 weeks GA 185-186

OXYGEN supplement

at 28 days in infants <33 weeks GA at Birth by units and GA groups 133-134

at discharge or Death in infants < 33 weeks GA by unit and GA group (graph) 139-140

at 36w PMA in infants <33 weeks GA at Birth by units and GA groups 136-137

at discharge or Death in infants < 33 weeks GA by unit and GA group 142-143

by BW in infants < 1500 gr Birthweight in ≥ 36w PMA at discharge in EpicLatino 2019 70-71

Median Days Regression in infants <33 weeks GA at > 2000m over sea level. by Units 188

< 2000m over sea level. by Units 190

Odds Ratio

at 28 days of birth in UNITS ≥ 2000 m over sea level Adjusted by SNAPEPE II and GA in < 33 w GA  146-147

< 2000 m over sea level Adjusted by SNAPEPE II and GA in < 33 w GA 145

at 36 weeks (By UNITS)

at ≥ 2000 m over sea level, Adjusted by SNAPEPE II and GA in < 33 weeks GA at birth 150-151

at discharge or DEATH in UNITS < 2000 m over sea level, Adjusted by SNAPEPE II and GA (By UNITS) IN < 33 WEEKS GA  152-153

≥ 2000 m over sea level, Adjusted by SNAPEPE II and GA (By UNIT) in < 33 w GA 154-155

< 2000 m over sea level Adjusted by SNAPEPE II and GA in < 33 w GA 148- 149

Patent Ductus Arteriosus

Presence and treatment by BW in EpicLatino 2019 52-55

by GA at birth 49

Type of Treatment by GA at birth in EpicLatino 2019 50-51

Periventricular and Intraparenchymal Hemorrhage (by GA at birth) TOTAL 61

Pneumothorax in EpicLatino 2019 46-47

Probiotics in EpicLatino 2019 46-47

RDS in EpicLatino 2019 46-47

Reanimation by GA < 31 weeks in EpicLatino 2019 34

Reanimation by GA ≥31 weeks 36

Red Blood Cells Packed Transfused (in infants <33 weeks GA) by Unit 198-199

Odds Ratio in ≤ 32 weeks GA at Birth controlled by SNAPEPE II and GA incremental graph 200-201

Respiratory Support Requirement at Discharge in Infants <1500 gr Birthweight in survivals to 36w PMA 72-73

by GA in infants < 33 weeks in survivals to 36w PMA 68-69

Retinopathy of Prematurity (ROP)

Stages ≥ III or Death in infants with BW ≤ 1500 grs ODDS RATIO controlled by SNAPEPE II and GA 165-166

Stages ≥ III or Death in infants with BW ≤ 1500 grs 164

≤ 32w (by GA) 74-75

by Birthweight in < 1500 gr 76-77

Stages in all Patients with ophthalmic examination 160

Therapy 163

Seizures 46-47

Sepsis

Early Onset by Birthweight < 3 days of birth/Admission 40-41

by GA in < 3 days of birth/Admission 38-39

Late Onset or Associated with Health Care

Crude Incidence of in Infants < 33 weeks GA  (Frequency by UNIT) 107-108

Odds Ratio in in < 33w GA Adjusted by SNAPEPE II and GA (Comparison by UNITS) 109-110

by BW  44-45

by GA 42-43

per 1000 Catheter Days in infants < 33 weeks GA 113- 114

per 1000 Patient Days in infants < 33 weeks GA 111-112

SNAP AND SNAPPE II NICUs in EpicLatino 2019 21

Steroids POSTNATAL in Infants < 33 weeks GA, Route and Indication 158

Steroids PRENATAL Use and Duration of in Mothers of Infants < 34 weeks GA 156

Structure of the neonatal Epiclatino network 1

Surfactant 46-47

Survival

by Birthweight 29-30

by Gestational Age at birth 26-27

Crude Frequency by GA and Unit  90-92

by Birthweight  95-98

Time of Stay IN Hospital for Infants Discharged Home in < 33 weeks GA 202

Total Parenteral Nutrition (TPN) Regression and Median ± IQR of Days with (in infants GA <33 weeks) by Unit 192-193

Ventriculomegaly in Patients with Neuroimaging by GA at birth 59-60

Z-SCORE Median drop in preterm babies < 1500 gr between birthweight and weight at discharge home, using Fenton 2013 curves 167